Biomedical Science: Recent submissions
Now showing items 21-40 of 41
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Prevalence, molecular pathotypes, clinical outcomes and antibiotic profiles of escherichia coli, salmonella and shigella from diarrhoea inpatients aged below five years at Moi Teaching and Referral Hospital
(Maseno University, 2015)Diarrhoea remains a major cause of mortality and morbidity worldwide. Diarrhoea in low income settings is attributed to bacterial enteropathogens but viruses and parasites may also be involved. Children infected with HIV ... -
Validation of Gene xpert and lam using urine from Hiv patients with clinical signs for diagnosis of Tuberculosis attending the Moi teaching and referral hospital Eldoret Kenyan
(Maseno University, 2016)Tuberculosis (TB) and HIV co-infections have a global prevalence with high morbidity and mortality and Africa is the worst hit. The HIV and AIDS has profound impact on the TB epidemic in Kenya, where up to 60% of TB patients ... -
Antibody Responses to Plasmodium Falciparum Antigens in Hiv Infected Adults in Bondo Sub County Hospital, Siaya County, Kenya
(Maseno University, 2016)Malaria and human immunodeficiency virus (HIV) are co-endemic in sub-Saharan Africa. Infection with HIV results in B cell anomalies. Antibodies are critical in protection against malaria and it is hypothesized that B cell ... -
Interaction between shigella flexneri and intestinal epithelial cells co-infected with selected enteric bacteria
(Maseno University, 2015)Bacteria, intestinal epithelium, and host innate immune responses are among the most critical interacting factors that determine the fate of bacterial infections and disease outcomes. Recent studies have described multiple ... -
Expression of cd23 by schistosoma mansoni antigen-activated b cells of highly exposed adult males on the shores of lake Victoria, Western Kenya
(Maseno University, 2016)Increased B cell membrane CD23 (low affinity IgE receptor) and its soluble cleavage product (sCD23) is related to the development of resistance to re-infection with Schistosoma mansoni. CD23 occurs as two isoforms (CD23a ... -
Development of antibody dependent respiratory burst assay as a tool for evaluating cellular immunity to malaria
(Maseno University, 2016)Malaria vaccine clinical trials in exposed populations have not always been consistent in finding robust associations between the predicted immune responses and protection against disease. The selection of most promising ... -
Effect of maternal plasmodium falciparum malaria infection during pregnancy on trans-placental transfer of Epstein Barr virus-specific igG antibodies, fetal lymphocyte homeostasis and cytokines in Chulaimbo
(Maseno University, 2015)Co-infection with malaria and Epstein Barr virus (EBV) have been implicated in the etiology of endemic Burkitt’s lymphoma (eBL) but the precise mechanism by which these two agents lead to the pathogenesis of eBL has been ... -
Serum electrolyte changes associated with kidney and liver function markers in HIV-infected individuals attending Jaramogi Oginga Odinga teaching and referral hospital, Kisumu county, kenya
(Maseno University, 2016)Serum electrolytes disorders in HIV patients in addition to resulting from disease induced fluids losses or accumulation could be attributed to a wide range of structural defects of cellular apparatus, tissue or organs ... -
Evaluation of the performance of Sacace HPV genotypes 14 real-tm quant and Carehpv against linear array in detection of human Papilloma virus genotypes in women from Western Kenya
(Maseno University, 2018)Cervical cancer (CC) is common among women, with global estimates of over 530,000 new cases and over 270,000 deaths annually. Human papilloma virus (HPV) infection increases the risk for CC development while high HIV ... -
Polymorphisms of toll like receptor 4 (-8984c/g and 299asp/gly) and Interferon gamma levels in children with severe Plasmodium Falciparum malaria Anaemia in Siaya county, Western Kenya
(Maseno University, 2018)Plasmodium falciparum (P. falciparum) malaria is a major cause of childhood morbidity and mortality in Sub-Saharan Africa despite the integrated approaches put in place to control the disease. Most of the mortality in ... -
Association between Ifn-γ, Tnf-α, Fcγriia and il-12β gene Polymorphisms and Susceptibility to Endemic Burkitt Lymphoma in children from Western Kenya
(Maseno University, 2018)Endemic Burkitt lymphoma (eBL) is an aggressive paediatric B-cell lymphoma prevalent in children from holoendemic malaria regions of sub-Saharan Africa. It is associated with early primary Epstein-Barr virus (EBV) and ... -
Spatial distribution and Schistosomes infection prevalence of Biomphalaria snails along Lake Victoria shoreline of Mbita - Homa-bay county-Kenya
(Maseno University, 2016)Intestinal schistosomiasis caused by Schistosoma mansoni remains a major public health problem responsible for morbidity and mortality in sub-Saharan Africa despite availability of control programs. It is estimated that ... -
An evaluation of Bacteriological quality of Water from ready-to-eat food outlets in Maseno Township, Western Kenya
(Maseno University, 2016)Water is a commodity which is essential for life as it has long been singled out globally as the most important factor in sustaining human health. Among other factors linked to human health; water has been implicated in ... -
Efficacy of Chlorfenapyr and Clothianidin Insecticides on Anopheles Malaria Vector populations of Nyando, Bumula and Ndhiwa sub-counties, Western Kenya
(Maseno University, 2018)Malaria is a global health problem resulting in 435,000 deaths annually with 90% of the deaths occurring in sub-Saharan Africa. Over 70% of the Kenyan population is at risk of malaria and western Kenya is an endemic region ... -
Clinical equivalence of heparinized arterial plasma to venous Serum for magnesium and phosphate measurement among Patients admitted at the intensive care unit of Moi teaching and referral hospital
(Maseno University, 2018)Electrolytes routinely measured in patients in Intensive Care Unit (ICU) are sodium, potassium, chloride, calcium, magnesium and phosphate. Of these; sodium, potassium, chloride and calcium are measured as part of tests ... -
Prevalence and intensity of the common Parasitic infections and Anaemia in street children compaired to school going children in Kisumu city, Kenya.
(Maseno University, 2018)The provision of skilled care during delivery is an indicator to monitor progress in reducing maternal mortality and falls in Goal 3 of the Sustainable Development Goals (SDGs). However, the proportion of Skilled Birth ... -
Association between genetic variations in selected cell receptors and nuclear transcription factors and susceptibility to Paediatric p. Falciparum severe malaria Anaemia in Siaya county, Western Kenya
(Maseno University, 2018)ABSTRACT Plasmodium falciparum severe malaria aneamia [SMA, haemoglobin (Hb) <5.0 g/dL or Hb<6.0 g/dL with any parasite density] remains the most life-threatening malaria. With its immuno-genetic basis partially understood, ... -
Phenotypic characterization of virulence, evolutionary Relationship and global expansion in Trypanosoma evansi isolates from Surra endemic regions
(Maseno University, 2018)ABSTRACT Trypanosoma evansi parasite is the causative agent of trypanosomiasis (surra) in camels and other livestock with devastating economic consequences in many parts of the world, including Kenya, Vietnam, Brazil, ... -
Effect of knockdown resistance on plasmodium falciparum sporozoite rates in malaria vectors in western Kenya
(Maseno University, 2017)