Browsing Biomedical Science by Issue Date
Now showing items 1-20 of 41
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Use of conventional and molecular techniques to Determine the prey alence of shigella and Enteroinv asive escherichia coli strains from Diarrhoea patients in selected health facilities in Rural western Kenya
(Maseno university, 2009)Diarrhoea is a major cause of infant morbidity and mortality worldwide. It accounts for 1.6- 2.5 million deaths annually and each child in the developing world experiences an average of three episodes of diarrhoea per ... -
Molecular analysis of HIV mutations and determination Of subtypes circulating in gem, western Kenya
(Maseno university, 2010)As the HIV pandemic becomes increasingly complex and devastating in Africa, there is need to come up with better management strategies in terms of treatment, vaccine and better testing methods. However, this is getting ... -
Immunophenotypic Characterization of Lymphocyte Subsets -Expressing Programmed Death-L (Pd-L) in Individuals Exposed to Differential Malaria Transmission Patterns and Endemic Burkitt's Lymphoma
(Maseno University, 2011)Repeated..challenge'of the immune system by chronicexposure to high antigen.levels due to persistent infection may lead to development of impaired T-cells that are not effective in . . . . .' \ mediatingimmune functions. ... -
Mechanisms Responsible for Insecticide Resistance in Anopheles Gambiae S.L. Populations of AHERO, BUDALANGI and BUNGOMA in Western Kenya
(Maseno University, 2011)As malaria control interventions directed against Anopheles vectors through the distribution of insecticide-treated bednets (ITNs) and application of indoor residual sprays (IRS) increase in sub-SaharanAfrica, it is crucial ... -
Evaluation of the Repellency Effectiveness of Linalool and Metofluthrin against Anopheles Gambiae S.L. in Kisian Village, Western Kenya
(Maseno University, 2012)Malaria continues to pose a major public health threat. Despite the efforts that have been made to prevent humans from mosquito bites, changes in the vector biting behavior, and mosquitoes tending to bite earlier before ... -
Lack of Association between Interleukin-6 (-174g/C),Interleukin-Io (-1082a/G, -819c/T, And -592c/A) Polymorphisms and Susceptibility to Endemic Burkitt Lymphoma in Children Aged between 5-8 Years from Western Kenya
(Maseno University, 2013)Endemic Burkitt lymphoma (eBL) is the most common paediatric cancer in sub-Saharan Africa and occurs at a high incidence in western Kenya. The tumour has the highest proliferative rate of any other human cancer. Although ... -
Associations between Functional Variations in Fc'yriiia and TLR 9 and Susceptibility to Severe Malaria Anemia in Cidldren below 3 Years in Western Kenya
(Maseno University, 2013)Plasmodium Jalciparum malaria in holoendemic transmission areas is a major cause of childhood morbidity and mortality. The greatest burden of this morbidity and mortality is as a consequence of severe malaria anemia (SMA) ... -
Comparison of hepatitis B virus sero-markers, clinical stages and genotypes between HIV-1 infected and uninfected injecting substance users in Mombasa city, Kenya
(Maseno University, 2015)Globally, it is estimated that 1.2 million injecting substance users are HBV infected while 1.7 million live with HIV. Africa is home to about 1.02 million injecting substance users of whom 12.7% are HBV infected while ... -
Interaction between shigella flexneri and intestinal epithelial cells co-infected with selected enteric bacteria
(Maseno University, 2015)Bacteria, intestinal epithelium, and host innate immune responses are among the most critical interacting factors that determine the fate of bacterial infections and disease outcomes. Recent studies have described multiple ... -
Prevalence, molecular pathotypes, clinical outcomes and antibiotic profiles of escherichia coli, salmonella and shigella from diarrhoea inpatients aged below five years at Moi Teaching and Referral Hospital
(Maseno University, 2015)Diarrhoea remains a major cause of mortality and morbidity worldwide. Diarrhoea in low income settings is attributed to bacterial enteropathogens but viruses and parasites may also be involved. Children infected with HIV ... -
Comparison of perfomance and factors that affect circulating cathodic antigen, kato-katz and elisa tests for schistosoma mansoni diagnosis in school children in Western Kenya
(Maseno University, 2015)Schistosomiasis infects approximately 207 million people worldwide with 90% of the cases occurring in Africa. Kato-Katz, is the standard method of S.mansoni diagnosis, however it is characterized by low sensitivity. Another ... -
Effect of maternal plasmodium falciparum malaria infection during pregnancy on trans-placental transfer of Epstein Barr virus-specific igG antibodies, fetal lymphocyte homeostasis and cytokines in Chulaimbo
(Maseno University, 2015)Co-infection with malaria and Epstein Barr virus (EBV) have been implicated in the etiology of endemic Burkitt’s lymphoma (eBL) but the precise mechanism by which these two agents lead to the pathogenesis of eBL has been ... -
Prevalence, source tracking and antimicrobial resistance of selected pathogenic bacteria in street vended foods sold in Kisumu city, Western Kenya
(Maseno University, 2015)The street food industry plays an important role in developing countries by meeting the food demand of the urban dwellers. There is an increase of food vending in Kisumu city due to poor economy and un-employment. Street ... -
Expression of cd23 by schistosoma mansoni antigen-activated b cells of highly exposed adult males on the shores of lake Victoria, Western Kenya
(Maseno University, 2016)Increased B cell membrane CD23 (low affinity IgE receptor) and its soluble cleavage product (sCD23) is related to the development of resistance to re-infection with Schistosoma mansoni. CD23 occurs as two isoforms (CD23a ... -
Multiple cytokine responses to mycobacterium tuberculosis antigens in bacille calmette guerrin vaccinated children at Jaramogi Oginga Odinga teaching and referral Hospital in KIsumu county, Western Kenya.
(Maseno University, 2016)The diagnosis and control of tuberculosis (TB) has taken various dimensions with interferon Gamma (IFN-γ) Release Assays (IGRA) currently employed for diagnosis of latent TB infection while the conventional method of ... -
Spatial distribution and Schistosomes infection prevalence of Biomphalaria snails along Lake Victoria shoreline of Mbita - Homa-bay county-Kenya
(Maseno University, 2016)Intestinal schistosomiasis caused by Schistosoma mansoni remains a major public health problem responsible for morbidity and mortality in sub-Saharan Africa despite availability of control programs. It is estimated that ... -
Serum electrolyte changes associated with kidney and liver function markers in HIV-infected individuals attending Jaramogi Oginga Odinga teaching and referral hospital, Kisumu county, kenya
(Maseno University, 2016)Serum electrolytes disorders in HIV patients in addition to resulting from disease induced fluids losses or accumulation could be attributed to a wide range of structural defects of cellular apparatus, tissue or organs ... -
An evaluation of Bacteriological quality of Water from ready-to-eat food outlets in Maseno Township, Western Kenya
(Maseno University, 2016)Water is a commodity which is essential for life as it has long been singled out globally as the most important factor in sustaining human health. Among other factors linked to human health; water has been implicated in ... -
Plasmodium Falciparum Malaria Transmission Effects on Natural Killer Cell Function in the Etiology of Endemic Burkitt Lymphoma in Children From Western Kenya
(Maseno University, 2016)ABSTRACT The exact etiological mechanism underlying endemic Burkitt lymphoma (eBL) remains unknown. Past studies show T and B cells are immuno-deregulated in children from malaria holoendemic regions. However, no study ... -
Validation of Gene xpert and lam using urine from Hiv patients with clinical signs for diagnosis of Tuberculosis attending the Moi teaching and referral hospital Eldoret Kenyan
(Maseno University, 2016)Tuberculosis (TB) and HIV co-infections have a global prevalence with high morbidity and mortality and Africa is the worst hit. The HIV and AIDS has profound impact on the TB epidemic in Kenya, where up to 60% of TB patients ...