Browsing Department of Medical Physiology by Issue Date
Now showing items 1-20 of 23
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Isolation, identification and characterization of urinary tract infectious bacteria and the effect of different antibiotics
(Journal of Natural Sciences Research, 2013)Introduction: Urinary Tract Infection (UTI) defines a condition in which the urinary tract is infected with a pathogen causing inflammation which is a common, distressing and occasionally life threatening condition. UTI ... -
Effects of crude extracts of Solanum nigrum on the Liver pathology and Survival time in Trypanosoma brucei rhodesiense infected mice
(Science Journal Publication, 2013)Tissue inflammatory damage during trypanosomosis significantly affects the treatment and prognosis. The current study investigated the effects of water extracts of Solanum nigrum (SNE) on the liver pathology and survival ... -
Comparison of drug Sensitivity and Pathogenicity of Trypanosoma brucei rhodesiense isolates with their respective clones originating from Busia and Busoga
(Journal of Natural Sciences Research, 2013)Introduction: Studies using clones in the laboratory show variations in pathogenicity and drug sensitivity compared to their respective natural isolates for various trypanosome species. This suggests that within isolates there ... -
In-vitro activity of artemether, lumefantrine, dihydroartemisinin and piperaquine against Plasmodium falciparum clinical isolates transported in a formulated transport medium
(Journal of Natural Sciences Research, 2016)Introduction: Development of resistance to antimalarials has emerged as one of the greatest challenges facing malaria control today. In vitro drug sensitivity relies on the growth of plasmodium in the presence of ... -
Sensitivity of 3D7 and W2 Clones in a Formulated Transport Medium and EDTA Anticoagulants against a Panel of Antimalarials
(Journal of Biology, Agriculture and Healthcare, 2016)Introduction: in vitro drug sensitivity relies on the growth of plasmodium in the presence of the antimalarials. These fresh isolates brought in for assay from collection sites normally not near the laboratory require a ... -
Phytochemical and Antiepileptic Activity of the Ethanol Leaf Extracts of Culcasia falcifolia in Pentylenetetrazole Induced Seizure in Mice
(Annual Research & Review in Biology, 2018)m: To investigate the phytochemicals and the anticonvulsant activity of the ethanol leaf extract of Culcasia falcifolia used in the traditional medical treatment of epilepsy. Methodology: The phytochemical screening was ... -
PhytochemicalandAntiepilepticActivityoftheEthanolLeafExtractsofCulcasiafalcifoliainPentylenetetrazoleInducedSeizureinMice
(Annual Research & Review in Biology, 2018)ToinvestigatethephytochemicalsandtheanticonvulsantactivityoftheethanolleafextractofCulcasiafalcifoliausedinthetraditionalmedicaltreatmentofepilepsy.Methodology:Thephytochemicalscreeningwascarriedoutusingstandardprotocolw ... -
Combined chemotherapy manifest less severe immunopathology effects in helminth-protozoa comorbidity
(Experimental parasitology, 2019)Background Co-infection with Leishmania major and Schistosoma mansoni may have significant consequences for disease progression, severity and subsequent transmission dynamics. Pentavalent antimonials and Praziquantel (PZQ) ... -
Haematological Parameters by Age and Sex of Asymptomatic Indigenous Cattle and Sheep Infected with Gastrointestinal Parasites in Kerio Valley, Kenya
(Science & Education Publishing, 2019)Gastro-intestinal parasites are prevalent and directly impede livestock production causing impaired productivity. Haematological parameters, which are likely to be influenced by parasites, are generally indicators of healthy ... -
Microscopy Underestimates the Prevalence of Trypanosomes’ Infection in Asymptomatic Cattle and Sheep in a Lowland Area within the Kenyan Rift Valley
(Scientific Research Publishing, 2019)Animal trypanosomosis continues to impede animal production in sub-Saharan Africa mostly in locations where tsetse flies are endemic. This has ended up devastating many livelihoods where majority of the people depend on ... -
Identity, Preparation, Dosages and Conservation Knowledge of the Antidiabetic Herbs Used by The Tugen Living in Baringo County-Kenya
(African Journal of Health Sciences, 2020)The primary goal of managing Diabetes Mellitus (DM) is to regulate blood sugar levels within the physiologic limits (3Mmol/l to7Mmmol/l-fasting blood sugars). This can be either done pharmacologically (conventional or ... -
May Measurement Month 2018: an analysis of blood pressure screening from Kenya
(ESC, 2020)Hypertension (HTN) is highly prevalent and the leading cardiovascular risk factor for death globally. A large proportion of individuals with high blood pressure (BP) are unaware leading to under treatment and poor control. ... -
Risk Of Transmission Of Hepatitis B And C Virus Through Blood Transfusion Due To Screening Methods At The National Blood Transfusion Centre In Nairobi, Kenya
(International Journal of Innovative Research and Advanced Studies(IJIRAS), 2020)The purpose of this study is to highlight the risk of transmitting HBV and HCV in blood banks in Kenya. This was a center based cross-sectional study. A total of 600 samples for blood donors attending the Regional ... -
Effects of Allium Sativum Ethanolic Extract on Trypanosoma brucei brucei Parasites’ Morphometric Parameters and Clinical Outcome in White Albino Laboratory Rats
(African Journal of Health Sciences, 2021)Background: Trypanosomosis affects humans as well as wild and domestic vertebrates, yet has no successful prophylaxis, chemotherapy nor cure. Objectives: The study was to investigate the effects of Allium sativum extract ... -
Intensity, duration and frequency of exercise needed to achieve change in metabolic profiles in prediabetes at Moi Teaching and Referral Hospital in Uasin Gishu County in Kenya
(East African Medical Journal, 2021)Objective: To establish the intensity, duration and frequency of exercise needed to achieve change in metabolic profiles of pre-diabetes at Moi Teaching and Referral Hospital, Eldoret, Kenya. Design: A randomized ... -
Acceptability and feasibility of inter-related activities to improve agency among African district health managers: A four-country study
(Taylor and Francis online, 2021)District health managers (DHMs) lead and manage Ministry of Health programmes and system performance. We report on the acceptability and feasibility of inter-related activities to increase the agency of DHMs in Kenya, ... -
Acceptability and feasibility of inter-related activities to improve agency among African district health managers: A four-country study
(Taylor and Francis online, 2021)District health managers (DHMs) lead and manage Ministry of Health programmes and system performance. We report on the acceptability and feasibility of inter-related activities to increase the agency of DHMs in Kenya, ... -
Immunohistochemical Analysis of Prostein in Needle Core Biopsies of Acinar and Intraductal Prostatic Adenocarcinoma in Western Kenya Population
(Fortune Journals, 2022)Prostein is a newly reported prostate cancer biomarker. Nonetheless, no reports on African population are available. The current study aimed to determine the prostein expression in archived prostatic core biopsies in Western ... -
Expression of IL-6 receptor correlates with Gleason grade for patients with prostatic acinar adenocarcinoma in Kisumu Specialist Hospital in Kisumu County, Western Kenya
(2022)The potential roles of inflammatory makers in prostate cancer are subjects of intense examination and Interleukin-6 receptor (IL-6R) is key in these processes. Expression of interleukin-6 Receptor (IL-6R) has not been ... -
Association between prostein immune-histochemical expression and histo-pathological grading of prostate cancer urology clinics in Kisumu city experience
(AJOL, 2022)The degree of morphological differentiation on histological assessment is a limited prediction of PCa aggressiveness. Prostein is being evaluated as additional biomarker in diagnosis and prognostication of prostate cancer.
