Browsing Paediatrics and Child Health by Issue Date
Now showing items 1-20 of 39
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Clinical cascades as a novel way to assess physical readiness of facilities for the care of small and sick neonates in Kenya and Uganda
(PLOS, 2018)Background Globally, there were 2.7 million neonatal deaths in 2015. Significant mortality reduction could be achieved by improving care in low- and middle-income countries (LMIC), where the majority of deaths occur. ... -
Risk factors for hypertension among young adults (18-35) years attending in Tenwek Mission Hospital, Bomet County, Kenya in 2018
(The pan African medical journal, 2019)hypertension ranks third in the world, after underweight and unsafe sex, in the list of six major risk factors contributing to the global disease. In Kenya, the prevalence stands at 24% in the general population, while ... -
Safety profile of the RTS, S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
(Taylor & Francis, 2019-10-03)A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS, S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children ... -
Immunophenotypic Characterization of ART- naive, HIV Infected Adults in Kombewa Sub-county, Kisumu: A Cross Sectional Study of Rural Population in Western Kenya
(Journal of Clinical Immunology and Research, 2020)Reliable information on clinical immunophenotypic biomarkers is critical in the management of Hepatitis B and C infections especially in ART naive HIV positive adults. CD4 cell counts and the level of liver function ... -
Case Report: An unusual case of bee envenomation presenting with acute kidney injury, cavernous venous thrombosis and multiple episodes of convulsions
(peertechzpublications, 2020)Bee stings are common in the tropics and cause minor problems but may occasionally cause severe anaphylactoid reactions -
The paediatrician workforce and its role in addressing neonatal, child and adolescent healthcare in Kenya
(BMJ, 2020)To examine the availability of paediatricians in Kenya and plans for their development. -
Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries
(The American Society of Tropical Medicine and Hygiene, 2020)RTS,S/AS01E malaria vaccine safety, effectiveness, and impact will be assessed in pre- and post-vaccine introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinate ... -
Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa
(Elsevier, 2020-01-22)We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of children identified as HIV-infected during a large phase III randomized controlled trial conducted in seven sub-Saharan African ... -
Estimating annual fluctuations in malaria transmission intensity and in the use of malaria control interventions in five sub-Saharan African countries
(The American Society of Tropical Medicine and Hygiene, 2020-11)RTS, S/AS01 E malaria vaccine safety, effectiveness, and impact will be assessed in pre-and post-vaccine introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinated ... -
Case Report: An unusual case of bee envenomation presenting with acute kidney injury, cavernous venous thrombosis and multiple episodes of convulsions
(Peertechz, 2020-11-07)Bee stings are common in the tropics and cause minor problems but may occasionally cause severe anaphylactoid reactions. Summary of clinical case: We present a case of M.O.O., an 8-year-old boy who was stung three times ... -
Immunophenotypic Characterization of ART-naive, HIV Infected Adults in Kombewa Sub-county, Kisumu: A Cross Sectional Study of Rural Population in Western Kenya
(Journal of Clinical Immunology and Research, 2020-11-12)Reliable information on clinical immunophenotypic biomarkers is critical in the management of Hepatitis B and C infections especially in ART naive HIV positive adults. CD4 cell counts and the level of liver function ... -
Association between haematological parameters and sickle cell genotypes in children with Plasmodium falciparum malaria resident in Kisumu County in Western Kenya
(BioMed Central, 2020-12)Sickle cell disease (SCD) is a monogenic disorder due to point mutation in the β-globin gene resulting in substitution of Valine for Glutamic acid. The SCD is prevalent in P. falciparum endemic regions such as western ... -
Caffeine for the care of preterm infants in sub- Saharan Africa: a missed opportunity?
(BMJ Specialist Journals, 2021)In 2019, 2.4 million neonates (infants <28 days of age) died globally. Of these, over 80% were preterm infants (<37 weeks gestation), with the majority born in low- income and middle- income countries.1 Complications of ... -
Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya
(Springer, 2021)In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ... -
Differential Gene Expression in Host Ubiquitination Processes in Childhood Malarial Anemia
(Frontiers Media SA, 2021): Malaria remains one of the leading global causes of childhood morbidity and mortality. In holoendemic Plasmodium falciparum transmission regions, such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < ... -
Baseline incidence of meningitis, malaria, mortality and other health outcomes in infants and young sub-Saharan African children prior to the introduction of the RTS,S/AS01E malaria vaccine
(BioMed Central, 2021)The lack of background disease incidence rates in sub-Saharan countries where the RTS,S/AS01E malaria vaccine is being implemented may hamper the assessment of vaccine safety and efectiveness. This study aimed to document ... -
Caffeine for the care of preterm infants in sub-Saharan Africa: a missed opportunity?
(BMJ Specialist Journals, 2021)In 2019, 2.4million neonates (infants <28 days of age) died globally. Of these, over 80% were preterm infants (<37 weeks gestation), with the majority born in low-income and middle-income countries.1 Complications ... -
Factors influencing mothers’ decisions regarding obstetrical care in Western Kenya: a mixed-methods study
(BioMed Central, 2021)Siaya County in Western Kenya has one of the highest maternal mortality rates in Kenya. We sought to elucidate factors that influence mothers’ decisions regarding where to seek obstetrical care, to inform interventions ... -
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya
(Public Library of Science, 2021-01-14)To describe the patient population, priority diseases and outcomes in newborns admitted <48 hours old to neonatal units in both Kenya and Nigeria. -
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya
(Public Library of Science, 2021-01-14)Objective To describe the patient population, priority diseases and outcomes in newborns admitted <48 hours old to neonatal units in both Kenya and Nigeria. Study design In a network of seven secondary and tertiary level ...