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dc.contributor.authorCollins O Odhiambo, Walter Otieno, Christine Adhiambo, Michael M Odera, José A Stoute
dc.date.accessioned2020-11-18T06:27:44Z
dc.date.available2020-11-18T06:27:44Z
dc.date.issued2010
dc.identifier.urihttps://repository.maseno.ac.ke/handle/123456789/2811
dc.description.abstractSevere anemia due to Plasmodium falciparum malaria is a major cause of mortality among young children in western Kenya. The factors that lead to the age-specific incidence of this anemia are unknown. Previous studies have shown an age-related expression of red cell complement regulatory proteins, which protect erythrocytes from autologous complement attack and destruction. Our primary objective was to determine whether in a malaria-endemic area red cells with low levels of complement regulatory proteins are at increased risk for complement (C3b) deposition in vivo. Secondarily, we studied the relationship between red cell complement regulatory protein levels and hemoglobin levels.en_US
dc.publisherBioMed Centralen_US
dc.titleIncreased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemiaen_US
dc.typeArticleen_US


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