dc.contributor.author | Peter Sifuna, Mary Oyugi, Bernhards Ogutu, Ben Andagalu, Allan Otieno, Victorine Owira, Nekoye Otsyula, Janet Oyieko, Jessica Cowden, Lucas Otieno, Walter Otieno | |
dc.date.accessioned | 2020-11-18T05:50:38Z | |
dc.date.available | 2020-11-18T05:50:38Z | |
dc.date.issued | 2014 | |
dc.identifier.uri | https://repository.maseno.ac.ke/handle/123456789/2804 | |
dc.description.abstract | The Kombewa Health and Demographic Surveillance System (HDSS) grew out of the Kombewa Clinical Research Centre in 2007 and has since established itself as a platform for the conduct of regulated clinical trials, nested studies and local disease surveillance. The HDSS is located in a rural part of Kisumu County, Western Kenya, and covers an area of about 369 km2 along the north-eastern shores of Lake Victoria. A dynamic cohort of 141 956 individuals drawn from 34 718 households forms the HDSS surveillance population. Following a baseline survey in 2011, the HDSS continues to monitor key population changes through routine biannual household surveys. The intervening period between set-up and baseline census was used for preparatory work, in particular Global Positioning System (GPS) mapping. Routine surveys capture information on individual and households including residency, household relationships, births, deaths, migrations (in and out) and causes of morbidity (syndromic incidence and prevalence) as well as causes of death (verbal autopsy). The Kombewa HDSS platform is used to support health research activities, that is clinical trials and epidemiological studies evaluating diseases of public health importance including malaria, HIV and global emerging infectious diseases such as dengue fever. Formal data request and proposed collaborations can be submitted at [email protected].
Topic: hivdengue feverautopsycause of deathcensusesemerging communicable diseasesdemographyepidemiologic studiesinternship and residencykenyamalariamorbiditypublic health medicinecollaborationmigration of medical device or device componentsurveillance, medicalbirthclinical research | en_US |
dc.publisher | Oxford University Press | en_US |
dc.subject | The Kombewa HDSS has established itself as a platform capable of supporting regulated clinical trials (Phase I to Phase IV) to evaluate vaccines, drugs or diagnostic platforms for a variety of pathogens found in sub-Saharan Africa. The Kombewa HDSS has been used to support health research by generating sampling frames and developing successful recruitment and retention strategies for both paediatric and adult clinical studies. Household morbidity data from the Kombewa DSS reveal a high burden of malaria (184 cases/1000/year) with an estimated under-five mortality ratio of 118/1000 live births for 2013. Why was the HDSS set u | en_US |
dc.title | Health & demographic surveillance system profile: the Kombewa health and demographic surveillance system (Kombewa HDSS) | en_US |
dc.type | Article | en_US |